Gastric Cancer as An Industry: What It Looks Like Globally?

Gastric cancer continues to be one of the most prevalent and dangerous diseases, particularly in older males. As per the GLOBOCAN 2018 data, stomach cancer is the third most lethal malignancy and the fifth most frequent neoplasm, with an anticipated 783,000 fatalities in 2018. For this, Diet and Helicobacter pylori infection can be entirely blamed as they are prominent factors behind incidences resulting in mortality. 

Clinicians still anticipate seeing more cases of stomach cancer in the future due to aging and population growth, despite the fact that standardized incidence and mortality rates of stomach cancer have decreased over the previous century. Additionally, compared to other malignancies, the expense of managing stomach cancer per patient is typically higher. In 2017, stomach cancer had a total annual healthcare cost of approximately 20.6 billion USD across four continents: Asia (China, Japan, and Iran), Europe (Germany, France, Spain, U.K., and Italy), North America (the USA and Canada), and Australia.  

Next, unwinding the market involving treatment methods and equipment for dealing with gastric cancer further, we can clearly affirm that the gastric cancer industry is evolving rapidly, with new treatments and therapies constantly being developed. That apparently paves the way for a brighter future for the industry, as there is a lot of potential for its growth. Some of the most exciting new treatments include targeted therapies and immunotherapies, which offer a lot of potential for helping patients to overcome this disease. With the inclusion of several latest varieties of drugs, and a few lined up, the market undoubtedly is rising. In fact, The Global Gastric Cancer Market is expected to grow at a CAGR of around 14.80% during 2022-27.

Comprehending The Prevalence of Gastric Cancer Across Regional Terrain 

In affluent countries, stomach cancer diagnoses are relatively more common than in emerging economies. For instance, male incidence rates range from 20 per 100,000 in high-middle Human Development Index (HDI) countries to 6.6 per 100,000 in low-middle HDI countries.

Based on diverse traditions and geographies, stomach cancer incidence varies accordingly. Latin America and Eastern and Central Asia have the maximum incidence rates. As per the data published by NCBI, the average incidence of stomach cancer in East Asia is 32.1 per 100,000 men and 13.2 per 100,000 women. This frequency is 5.6 per 100,000 people in North America. North and East Africa had the lowest rate, with only 4.7 yearly diagnoses per 100,000 males. The Republic of Korea has over 60 percent of the country's occurrence. Meanwhile, the data seems promising to the stakeholders, particularly in the Asia-pacific region, looking forward to investing in or manufacturing the treatment equipment as the statics clearly hints at the emerging need to treat the mounting pool of patients.

Likewise, the approval of new targeted and immunotherapy treatments is foreseen as the catalyzer to the market. To give an example, the USA FDA authorized Opdivo (nivolumab) in April 2021 for the first management of patients with metastatic or advanced GC/GEJC. In a similar vein, the USA FDA authorized Enhertu in January 2021, an antibody-drug combination product for managing metastatic HER-2-positive gastric cancer. Such government initiatives set forth a suitable stage for the key players to showcase their potential to cater to stomach cancer patients worldwide.

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Tests And Procedures Involved in The Staging Process Are to Bring Along Opportunities for Investors

Endoscopic Ultrasound (EUS)

A procedure in which an endoscope is put into the body, typically through the mouth or rectum. It is a small, tube-shaped device containing a viewing lens and light. The endoscope's probe creates echoes by bouncing high-energy sound waves (ultrasound) off inside organs or tissues. In response to the need from medical practitioners for clear, high-quality images when performing endoscopic ultrasound procedures, Olympus has introduced the EU-ME3 Endoscopic Ultrasound Processor.

A CT scan (CAT scan) 

It creates sequential fine-grained images of specific body parts, such as the abdomen. An x-ray machine and a computer are connected to create the images. Envisioning its importance, Siemens Healthineers introduced the first photon-counting CT scanner, Naeotom Alpha, in 202. For ultra-high resolution (UHR) scans, the enhancements facilitated by photon counting include an increase in resolution and a radiation dose reduction of up to 45% compared to standard CT detectors without a UHR comb filter.

PET scan

A Positron Emission Tomography Scan locates the body's malignant tumor cells. A vein receives a tiny injection of radioactive glucose (sugar). The PET scanner spins around the body to provide an image of the areas of the body where glucose is being injected. Since malignant tumor cells are more active and absorb more glucose than healthy cells, they appear brighter in the image. For instance, Positron Corporation, a nuclear medicine PET imaging device system, and clinical services company, is delighted to reveal that its first PET-CT system, named Affinity PET-CT, launched in September 2022.

Available Treatment Therapies and Their Growth Prospects

Among all therapies, such as Chemotherapy, Surgery, Targeted Drug Therapy, and Immunotherapy, Surgery is the most opted one. Due to surgery's capacity to treat malignancies of all stages, patients with stomach cancer are increasingly gravitating toward it. Growing public awareness of the range of procedures available depending on factors like tumor size, location, patient health, etc., is another prominent factor backing the growth of the surgical industry.

On the other hand, there are three ways to administer chemotherapy to patients with stomach cancer:

Radiation therapy and neoadjuvant therapy, often known as preoperative care, are occasionally administered to patients (chemoradiation). The main goal of this treatment is to reduce the tumor's size so that it can be surgically removed with ease. It may also prevent cancer from returning. 

Next, Adjuvant therapy is used after surgery with the primary goals of eradicating any small-cell carcinoma that may still be present and preventing the possibility of recurrence in any region. After the surgery, radiation therapy is occasionally given in addition to chemotherapy. Lastly, If the tumor has spread to distant organs or cannot be removed for any other reason, chemotherapy is used as the primary treatment. In some situations, chemotherapy may aid in decreasing cancer or slowing the growth rate, extending the patient's life.

To Conclude

Since the global gastric cancer market witnessed abrupt growth, providers need to stay ahead of the curve to stay competitive. By understanding the different trends and dynamics, providers can ensure that they provide the best possible care to their patients. Moreover, regarding absolute burden, stomach cancer makes up a sizable portion of all cancers. In order to direct public policy and serve as a benchmark for decision-makers, and encourage investors and manufacturers, it is crucial to conduct a comparable, consistent, and comprehensive analysis of the long-term trends and patterns of stomach cancer worldwide.